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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2282
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Runx2
Name: RUNX family transcription factor 2
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Runx2multiple interactionsEXP 6480464CTDHydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]PMID:27028516
Runx2decreases expressionISORUNX2 (Homo sapiens)6480464CTDHydrogen Peroxide results in decreased expression of RUNX2 mRNAPMID:26482937
Runx2multiple interactionsISORUNX2 (Homo sapiens)6480464CTDDKK1 protein inhibits the reaction [naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]]; naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]PMID:26482937
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