GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cav1 | increases expression | ISO | Cav1 (Mus musculus) | 6480464 | CTD | 3,4,3',4'-tetrachlorobiphenyl results in increased expression of CAV1 protein | PMID:18786521 | Cav1 | multiple interactions | ISO | Cav1 (Mus musculus) | 6480464 | CTD | 3,4,3',4'-tetrachlorobiphenyl promotes the reaction [CAV1 protein binds to AHR protein]; CAV1 mutant form inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 protein]; CAV1 mutant form inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CAV1 mutant form inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CAV1 protein promotes the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein] | PMID:18786521 PMID:20406653 | | ||||||||||||||||||||||
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