Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Glucose results in increased expression of CASP3 mRNA; Glucose results in increased expression of CASP3 protein; Glucose results in increased expression of CASP3 protein modified form
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; [Dithionite co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [morroniside co-treated with Diosgenin] inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of and affects the activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP3]; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; cinnamic acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; cobaltiprotoporphyrin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Diosgenin inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; Glucose results in increased expression of and results in increased activity of CASP3 protein; Glucose results in increased expression of and results in increased cleavage of CASP3 protein; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; IGF2R protein modified form inhibits the reaction [Glucose results in increased expression of CASP3 protein modified form]; IGF2R protein modified form inhibits the reaction [Glucose results in increased expression of CASP3 protein]; KEAP1 protein inhibits the reaction [diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; Metformin inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Metformin inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; morroniside inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased activity of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein mutant form affects the reaction [plumbagin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]; plumbagin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP3 protein modified form]; sesamin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Simvastatin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; STIM1 protein affects the reaction [Glucose results in increased cleavage of CASP3 protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; WDR35 protein affects the reaction [Glucose results in increased activity of CASP3 protein]; Y 27632 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]
[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein; [Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP3 protein]; Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Glucose results in increased cleavage of and results in increased activity of CASP3 protein; HIF1A protein affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; HIF1A protein affects the reaction [MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]]; INO 1001 inhibits the reaction [Glucose results in increased activity of CASP3 protein]; MIR144 mRNA promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; MIR186 mRNA inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; MIR322 affects the reaction [Glucose results in increased cleavage of CASP3 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein]; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; TRAF3 affects the reaction [Glucose results in increased cleavage of CASP3 protein]; TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein]; VDAC1 protein inhibits the reaction [Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; VDAC1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [[Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein]
[Carnosine co-treated with asiatic acid] inhibits the reaction [Glucose results in increased activity of CASP3 protein]; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form; [Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein; asiatic acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Captopril inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; Carnosine inhibits the reaction [Glucose results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Fluorometholone inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Gliclazide inhibits the reaction [Glucose results in increased expression of CASP3 protein]; huai qi huang inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of CASP3 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein]; MitoTEMPO inhibits the reaction [Glucose results in increased activity of CASP3 protein]; polyethylene glycol loxenatide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Rosiglitazone inhibits the reaction [Glucose results in increased activity of CASP3 protein]; rutecarpine inhibits the reaction [Glucose results in increased activity of CASP3 protein]; salvianolic acid inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein]
