GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases expression | EXP | | 6480464 | CTD | Cytarabine results in increased expression of CASP3 protein | PMID:14766721 PMID:22212197 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Cytarabine results in increased activity of CASP3 protein | PMID:12781215 PMID:25003661 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | [Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein | PMID:12780785 PMID:8840993 | |
Go Back to source page | Continue to Ontology report |