GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp1 | affects localization | ISO | Casp1 (Mus musculus) | 6480464 | CTD | 7-ketocholesterol affects the localization of CASP1 protein | PMID:28633109 | Casp1 | increases activity | ISO | Casp1 (Mus musculus) | 6480464 | CTD | 7-ketocholesterol results in increased activity of CASP1 protein | PMID:28633109 | Casp1 | multiple interactions | ISO | Casp1 (Mus musculus) | 6480464 | CTD | Amitriptyline inhibits the reaction [7-ketocholesterol affects the localization of CASP1 protein]; Amitriptyline inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; methyl-beta-cyclodextrin inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; SMPD1 protein affects the reaction [7-ketocholesterol affects the localization of CASP1 protein]; SMPD1 protein affects the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; tempol inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; Verapamil inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein] | PMID:28633109 | | ||||||||||||||||||||||
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