GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp1 | increases cleavage | ISO | CASP1 (Homo sapiens) | 6480464 | CTD | Ropivacaine results in increased cleavage of CASP1 protein | PMID:36858639 | Casp1 | multiple interactions | ISO | CASP1 (Homo sapiens) | 6480464 | CTD | Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]] | PMID:36858639 | |
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