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GENE - TERM ANNOTATION REPORT

RGD ID: 2245
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cacna1c
Name: calcium voltage-gated channel subunit alpha1 C
Acc ID: DOID:9000064
Term: Cardiac Arrhythmias
Definition: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Definition Source(s): MESH:D001145
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cacna1c ISOCACNA1C (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:15454078
Cacna1c ISOCACNA1C (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Cardiac arrhythmiaPMID:24690944 PMID:25741868 PMID:26253506 PMID:27218670 PMID:28492532 PMID:30025578 PMID:30172029 PMID:31110529 PMID:31408100 PMID:31430211 PMID:32161207
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