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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2240
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Car2
Name: carbonic anhydrase 2
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Car2increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of CA2 mRNAPMID:19638242
Car2multiple interactionsEXP 6480464CTD[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CAR2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CAR2 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CA2 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CA2 mRNAPMID:14656948 PMID:16158176 PMID:18164116 PMID:28943392
Car2multiple interactionsISOCar2 (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CAR2 mRNAPMID:24535843
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