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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2202
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdnf
Name: brain-derived neurotrophic factor
Acc ID: CHEBI:134301
Term: salvianolic acid B
Definition: A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza
Chemical ID: MESH:C076944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdnfincreases expressionISOBdnf (Mus musculus)6480464CTDsalvianolic acid B results in increased expression of BDNF proteinPMID:24991814
Bdnfmultiple interactionsISOBdnf (Mus musculus)6480464CTDsalvianolic acid B inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein]PMID:24991814
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