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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:29014
Term: cordycepin
Definition: A 3'-deoxyribonucleoside that has formula C10H13N5O3.
Chemical ID: MESH:C058120
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2multiple interactionsEXP 6480464CTDcordycepin inhibits the reaction [testosterone enanthate results in increased expression of BCL2 mRNA]; cordycepin inhibits the reaction [testosterone enanthate results in increased expression of BCL2 protein]PMID:36015278
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDcordycepin results in decreased expression of BCL2 mRNA; cordycepin results in decreased expression of BCL2 proteinPMID:21310227 PMID:28987792 PMID:30529626 PMID:32730909
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD[cordycepin co-treated with apatinib] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2 protein]PMID:21310227 PMID:33014856
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