GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | ochratoxin A results in increased expression of BAX mRNA | PMID:23208426 | Bax | affects localization | ISO | BAX (Homo sapiens) | 6480464 | CTD | ochratoxin A affects the localization of BAX protein | PMID:20549612 | Bax | decreases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | ochratoxin A results in decreased expression of BAX mRNA; ochratoxin A results in decreased expression of BAX protein | PMID:19367635 PMID:24755393 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | ochratoxin A results in increased expression of BAX mRNA | PMID:36397609 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | ochratoxin A results in increased expression of BAX mRNA; ochratoxin A results in increased expression of BAX protein | PMID:20549612 PMID:31154016 PMID:33465424 PMID:34101318 PMID:34126166 PMID:36587836 | Bax | increases response to substance | ISO | BAX (Homo sapiens) | 6480464 | CTD | BAX protein results in increased susceptibility to ochratoxin A | PMID:20549612 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | [fumonisin B1 co-treated with ochratoxin A] results in increased expression of BAX protein; fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of BAX mRNA] | PMID:36397609 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [Aflatoxin M1 co-treated with ochratoxin A] results in increased expression of BAX protein; BNIP3L protein inhibits the reaction [ochratoxin A results in decreased expression of BAX mRNA]; Oleanolic Acid inhibits the reaction [ochratoxin A results in increased expression of BAX protein]; TRAP1 protein affects the reaction [ochratoxin A results in increased expression of BAX protein]; TRAP1 protein affects the reaction [Oleanolic Acid inhibits the reaction [ochratoxin A results in increased expression of BAX protein]]; Ursolic Acid inhibits the reaction [ochratoxin A results in increased expression of BAX protein] | PMID:24755393 PMID:33465424 PMID:34126166 PMID:36587836 | |
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