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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:75092
Term: morin
Definition: A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.
Chemical ID: MESH:C008548
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsEXP 6480464CTDmorin inhibits the reaction [Acetaminophen results in increased expression of BAX protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; morin inhibits the reaction [Doxorubicin affects the expression of BAX protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [titanium dioxide results in increased expression of BAX mRNA]PMID:19201465 PMID:19931519 PMID:26767949 PMID:28844848 PMID:31100273 PMID:35414346
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDmorin results in increased expression of BAX mRNAPMID:28689916
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