GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | celastrol results in increased expression of BAX mRNA; celastrol results in increased expression of BAX protein | PMID:21466843 PMID:27374097 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | [celastrol co-treated with coomassie Brilliant Blue] inhibits the reaction [Acetaminophen results in increased expression of BAX protein]; celastrol inhibits the reaction [Acetaminophen results in increased expression of BAX protein]; celastrol inhibits the reaction [Plant Preparations results in increased expression of BAX mRNA]; celastrol inhibits the reaction [Plant Preparations results in increased expression of BAX protein] | PMID:28435131 PMID:29643811 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | Uridine inhibits the reaction [celastrol results in increased expression of BAX protein] | PMID:27374097 | |
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