GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Bortezomib results in increased expression of BAX protein | PMID:20383943 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [Bortezomib co-treated with arsenic trioxide] affects the expression of BAX protein; [nutlin 3 co-treated with Bortezomib] results in increased activity of BAX protein; BAX results in increased susceptibility to [Bortezomib co-treated with panobinostat]; Bortezomib inhibits the reaction [BAX mutant form inhibits the reaction [TNFSF10 protein results in increased localization of DIABLO protein]] | PMID:12902978 PMID:18445700 PMID:18718063 PMID:20850924 | |
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