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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:50103
Term: excitatory amino acid agonist
Definition: An agent that binds to and activates excitatory amino acid receptors.
Chemical ID: MESH:D018690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDExcitatory Amino Acid Agonists results in increased expression of BAX proteinPMID:19201465
Baxmultiple interactionsEXP 6480464CTDDizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]PMID:19201465
Baxincreases expressionISOBax (Mus musculus)6480464CTDExcitatory Amino Acid Agonists results in increased expression of BAX proteinPMID:19224577
Baxmultiple interactionsISOBax (Mus musculus)6480464CTDnotoginsenoside R1 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]PMID:19224577
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