GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Epirubicin results in increased expression of BAX protein | PMID:26646421 PMID:29505745 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Epirubicin results in increased expression of BAX mRNA | PMID:22914566 PMID:23867903 PMID:26335193 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | paeonol inhibits the reaction [Epirubicin results in increased expression of BAX protein] | PMID:26646421 PMID:29505745 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of BAX mRNA]; [Epirubicin analog co-treated with chrysophsin analog] results in increased expression of BAX mRNA; chrysophsin promotes the reaction [Epirubicin results in increased expression of BAX mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of BAX mRNA]; Epirubicin promotes the reaction [chrysophsin results in increased expression of BAX mRNA]; formononetin promotes the reaction [Epirubicin results in increased expression of BAX mRNA] | PMID:22914566 PMID:23867903 PMID:26335193 | |
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