GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | Fluorouracil results in increased expression of BAX mRNA; Fluorouracil results in increased expression of BAX protein | PMID:16888818 PMID:38078205 | Bax | multiple interactions | EXP | | 6480464 | CTD | Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA] | PMID:31129132 | Bax | affects expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Fluorouracil affects the expression of BAX mRNA | PMID:23941782 | Bax | decreases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Fluorouracil results in decreased expression of BAX protein | PMID:11062132 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Fluorouracil results in increased expression of BAX protein | PMID:18567086 PMID:19116755 PMID:20844880 PMID:30542770 PMID:32270916 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Fluorouracil results in increased expression of BAX; Fluorouracil results in increased expression of BAX mRNA; Fluorouracil results in increased expression of BAX protein | PMID:11750847 PMID:12442003 PMID:15641988 PMID:15986848 PMID:17045692 PMID:17056233 PMID:17589894 PMID:19116755 PMID:22525470 PMID:25824412 PMID:28599477 PMID:29054700 PMID:31587439 PMID:9388485 PMID:9792140 | Bax | increases response to substance | ISO | BAX (Homo sapiens) | 6480464 | CTD | BAX protein results in increased susceptibility to Fluorouracil | PMID:11062132 PMID:16686938 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in increased expression of BAX protein; casticin inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; IL1RN protein affects the reaction [Fluorouracil results in increased expression of BAX protein] | PMID:18567086 PMID:20844880 PMID:32270916 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in increased expression of BAX mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of BAX protein; [SM-1 compound co-treated with Fluorouracil] results in increased expression of BAX protein; [wogonin co-treated with Fluorouracil] results in increased expression of BAX protein; Aspirin promotes the reaction [Fluorouracil results in increased expression of BAX protein]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BAX mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BAX mRNA]; Fluorouracil affects the reaction [rebamipide results in decreased expression of BAX protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of BAX protein]; Fluorouracil promotes the reaction [andrographolide affects the folding of BAX protein]; Fluorouracil promotes the reaction [Aspirin results in increased expression of BAX protein]; Fluorouracil promotes the reaction [Plant Extracts results in increased expression of BAX protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; SM-1 compound promotes the reaction [Fluorouracil results in increased expression of BAX mRNA] | PMID:15754201 PMID:15986848 PMID:16168113 PMID:17045692 PMID:18834353 PMID:19015929 PMID:19097688 PMID:20570612 PMID:23941782 PMID:28599477 PMID:29054700 PMID:31587439 PMID:32800223 | |
Go Back to source page | Continue to Ontology report |