GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | affects localization | EXP | | 6480464 | CTD | cypermethrin affects the localization of BAX protein | PMID:25370934 | Bax | increases expression | EXP | | 6480464 | CTD | cypermethrin results in increased expression of BAX mRNA; cypermethrin results in increased expression of BAX protein | PMID:22048644 PMID:22528246 PMID:35876585 | Bax | multiple interactions | EXP | | 6480464 | CTD | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of BAX mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of BAX mRNA; [fenvalerate co-treated with Allethrins co-treated with cypermethrin co-treated with decamethrin co-treated with cyhalothrin] results in decreased expression of BAX mRNA; Cyclosporine inhibits the reaction [cypermethrin affects the localization of BAX protein]; HBEGF protein inhibits the reaction [cypermethrin results in increased expression of BAX protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [cypermethrin affects the localization of BAX protein]; Quercetin inhibits the reaction [cypermethrin results in increased expression of BAX mRNA]; Quercetin inhibits the reaction [cypermethrin results in increased expression of BAX protein] | PMID:22048644 PMID:25370934 PMID:33396045 PMID:34896426 PMID:35876585 PMID:36053783 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | cypermethrin results in increased expression of BAX mRNA | PMID:29945211 PMID:32028016 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of BAX mRNA] | PMID:29945211 | |
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