GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | Cyclosporine results in increased expression of BAX; Cyclosporine results in increased expression of BAX mRNA; Cyclosporine results in increased expression of BAX protein | PMID:25299210 PMID:32569592 PMID:33710703 | Bax | multiple interactions | EXP | | 6480464 | CTD | Cyclosporine inhibits the reaction [cypermethrin affects the localization of BAX protein]; nilotinib inhibits the reaction [Cyclosporine results in increased expression of BAX mRNA]; nilotinib inhibits the reaction [Cyclosporine results in increased expression of BAX protein] | PMID:25370934 PMID:33710703 | Bax | decreases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Cyclosporine results in decreased expression of BAX mRNA | PMID:25562108 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Cyclosporine results in increased expression of BAX mRNA; Cyclosporine results in increased expression of BAX protein | PMID:20106945 PMID:25596134 PMID:35033536 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | Cyclosporine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Cyclosporine inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]]; Cyclosporine inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]]; Cyclosporine inhibits the reaction [Reactive Oxygen Species results in increased expression of BAX protein] | PMID:10205001 PMID:26884717 PMID:33689844 PMID:37308051 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | Cyclosporine inhibits the reaction [Reactive Oxygen Species results in increased expression of BAX protein] | PMID:26884717 | |
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