GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of BAX mRNA; perfluorooctane sulfonic acid results in increased expression of BAX protein | PMID:24616003 PMID:26844784 PMID:35934180 | Bax | decreases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | perfluorooctane sulfonic acid results in decreased expression of BAX mRNA | PMID:23562911 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of BAX mRNA; perfluorooctane sulfonic acid results in increased expression of BAX protein | PMID:21115943 PMID:23562911 PMID:34303733 PMID:36988283 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | perfluorooctane sulfonic acid results in increased expression of BAX mRNA; perfluorooctane sulfonic acid results in increased expression of BAX protein | PMID:22976841 PMID:26844784 PMID:32790152 PMID:34006824 PMID:36988283 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of BAX mRNA; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BAX mRNA]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BAX protein] | PMID:36331819 PMID:36988283 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [perfluorooctane sulfonic acid results in increased phosphorylation of and results in increased activity of MAPK8 protein] which affects the localization of BAX protein; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BAX mRNA]; Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of BAX protein]; MIR155 mRNA promotes the reaction [perfluorooctane sulfonic acid results in increased expression of BAX protein]; perfluorooctane sulfonic acid promotes the reaction [BAX protein binds to BAK1 protein]; perfluorooctane sulfonic acid promotes the reaction [BAX protein binds to PPID protein] | PMID:26844784 PMID:34006824 PMID:36988283 | |
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