GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | affects expression | EXP | | 6480464 | CTD | Paraquat affects the expression of BAX mRNA | PMID:15206577 | Bax | increases expression | EXP | | 6480464 | CTD | Paraquat results in increased expression of BAX mRNA; Paraquat results in increased expression of BAX protein | PMID:12714668 PMID:22678742 PMID:26887261 PMID:30088170 PMID:30112919 PMID:30403199 PMID:31128353 PMID:32680482 PMID:35236239 PMID:35707280 | Bax | multiple interactions | EXP | | 6480464 | CTD | [Paraquat co-treated with Decitabine] results in increased expression of BAX protein; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX protein]; Docosahexaenoic Acids inhibits the reaction [Paraquat results in increased expression of BAX protein]; fasudil inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; ginkgolide C inhibits the reaction [Paraquat results in increased expression of BAX protein]; MIR136 promotes the reaction [Paraquat results in increased expression of BAX protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Paraquat promotes the reaction [BAX protein binds to BAK1 protein]; Paraquat results in increased expression of and affects the localization of BAX protein; Resveratrol inhibits the reaction [MIR136 promotes the reaction [Paraquat results in increased expression of BAX protein]]; Resveratrol inhibits the reaction [Paraquat results in increased expression of BAX protein]; tanshinone II A sodium sulfonate inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; tanshinone II A sodium sulfonate inhibits the reaction [Paraquat results in increased expression of BAX protein] | PMID:12714668 PMID:22678742 PMID:22796470 PMID:25947082 PMID:30088170 PMID:30112919 PMID:30403199 PMID:35236239 PMID:35707280 | Bax | affects expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Paraquat affects the expression of BAX mRNA | PMID:27220436 | Bax | decreases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Paraquat results in decreased expression of BAX mRNA | PMID:18836921 PMID:26468117 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Paraquat results in increased expression of BAX mRNA; Paraquat results in increased expression of BAX protein | PMID:27442881 PMID:28115273 PMID:28480221 PMID:29054699 PMID:30171970 PMID:31368586 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Paraquat results in increased expression of BAX mRNA; Paraquat results in increased expression of BAX protein | PMID:18253895 PMID:26074776 PMID:26686574 PMID:27793699 PMID:30185695 PMID:31966674 PMID:32527420 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | [Maneb co-treated with Paraquat] results in increased expression of BAX mRNA; [Paraquat co-treated with Maneb] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX protein]; AKT1 protein affects the reaction [Paraquat results in increased expression of BAX protein]; GPX1 protein affects the reaction [Paraquat affects the expression of BAX mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in increased expression of BAX protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of BAX protein]; T0901317 inhibits the reaction [Paraquat results in increased expression of BAX protein] | PMID:12654481 PMID:20964710 PMID:23963992 PMID:28115273 PMID:28480221 PMID:29054699 PMID:30171970 PMID:31368586 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX protein]; [Paraquat co-treated with Maneb] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; BAX protein affects the susceptibility to [Paraquat co-treated with Maneb]; Curcumin inhibits the reaction [Paraquat results in increased expression of BAX protein]; DNAJC3 protein affects the reaction [Paraquat results in increased expression of BAX protein]; DNAJC3 protein inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; DNAJC3 protein inhibits the reaction [Paraquat results in increased expression of BAX protein]; Emulsions promotes the reaction [Quercetin inhibits the reaction [Paraquat results in increased expression of BAX mRNA]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased expression of BAX protein]; Quercetin inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; salvin inhibits the reaction [Paraquat results in increased expression of BAX protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX protein] | PMID:15824117 PMID:18266926 PMID:26074776 PMID:26686574 PMID:27793699 PMID:30171970 PMID:30185695 PMID:31966674 PMID:32527420 | |
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