GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | decreases expression | EXP | | 6480464 | CTD | Diethylnitrosamine results in decreased expression of BAX mRNA; Diethylnitrosamine results in decreased expression of BAX protein | PMID:19931519 PMID:22393308 PMID:30423403 PMID:31129132 PMID:35437842 | Bax | increases expression | EXP | | 6480464 | CTD | Diethylnitrosamine results in increased expression of BAX protein | PMID:19073162 PMID:21167192 | Bax | multiple interactions | EXP | | 6480464 | CTD | [2-aminofluorene co-treated with Diethylnitrosamine] results in increased expression of BAX protein; [5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of BAX protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein; [Diethylnitrosamine co-treated with Cyclohexanols] results in decreased expression of BAX protein; [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of BAX mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of BAX mRNA; chrysin promotes the reaction [Diethylnitrosamine results in increased expression of BAX protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; Plant Oils inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; Plant Oils inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; Resveratrol promotes the reaction [Diethylnitrosamine results in increased expression of BAX protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; zerumbone promotes the reaction [[2-aminofluorene co-treated with Diethylnitrosamine] results in increased expression of BAX protein]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein] | PMID:11915028 PMID:17393424 PMID:19073162 PMID:19931519 PMID:20452335 PMID:21167192 PMID:21554863 PMID:22393308 PMID:23830814 PMID:30423403 PMID:31129132 PMID:35437842 | Bax | decreases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in decreased expression of BAX protein | PMID:34726822 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in increased expression of BAX mRNA; Diethylnitrosamine results in increased expression of BAX protein | PMID:18056438 PMID:19100860 PMID:21607683 PMID:26464624 PMID:27553677 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of BAX mRNA]; maculosin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; Quercetin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein] | PMID:18056438 PMID:34726822 | |
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