Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:30146
Term: lithium hydride
Definition: An alkali metal hydride where the metal is specified as lithium.
Chemical ID: MESH:D008094
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsEXP 6480464CTDLithium inhibits the reaction [Cadmium results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Morphine results in increased expression of BAX mRNA]PMID:18976035 PMID:19149911 PMID:20455018
Baxdecreases expressionISOBAX (Homo sapiens)6480464CTDLithium results in decreased expression of BAX mRNAPMID:19949822
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX protein]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX protein; Lithium inhibits the reaction [sodium arsenite affects the localization of BAX protein]; Lithium inhibits the reaction [sodium arsenite promotes the reaction [BAX protein binds to BAX protein]]PMID:17849503 PMID:26074776
Go Back to source page   Continue to Ontology report