GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | multiple interactions | EXP | | 6480464 | CTD | [Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of BAX protein | PMID:27836789 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Gold results in increased expression of BAX mRNA | PMID:22178767 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of BAX protein; [Gold analog co-treated with Platinum] results in increased expression of BAX mRNA; [Polyethyleneimine binds to Gold] which results in decreased expression of BAX mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of BAX protein | PMID:21621595 PMID:25846798 PMID:27470402 PMID:28433809 | |
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