Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:30050
Term: gold(0)
Definition: An elemental gold that has formula Au.
Chemical ID: MESH:D006046
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsEXP 6480464CTD[Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of BAX proteinPMID:27836789
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDGold results in increased expression of BAX mRNAPMID:22178767
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of BAX protein; [Gold analog co-treated with Platinum] results in increased expression of BAX mRNA; [Polyethyleneimine binds to Gold] which results in decreased expression of BAX mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of BAX proteinPMID:21621595 PMID:25846798 PMID:27470402 PMID:28433809
Go Back to source page   Continue to Ontology report