GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | Nickel analog results in increased expression of BAX protein; Nickel results in increased expression of BAX protein | PMID:21417627 PMID:27257140 | Bax | multiple interactions | EXP | | 6480464 | CTD | Grape Seed Proanthocyanidins inhibits the reaction [Nickel results in increased expression of BAX protein] | PMID:21417627 | Bax | affects expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Nickel analog affects the expression of BAX protein | PMID:23776134 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Nickel results in increased expression of BAX mRNA | PMID:24768652 PMID:25583101 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [cobalt ferrite binds to Nickel] which results in increased expression of BAX protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein; [nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein; Luteolin affects the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein]; Nickel results in increased expression of and results in increased cleavage of BAX protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein] | PMID:29115570 PMID:31943712 PMID:31953414 PMID:36073959 | |
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