Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:17933
Term: calcidiol
Definition: A hydroxycalciol that is calciol in which the hydrogen at position 25 has been replaced by a hydroxy group. A prehormone resulting from the oxidation of calciol in the liver, it is further hydroxylated in the kidney to give calcitriol, the active form of vitamin D3.
Chemical ID: MESH:D002112
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxdecreases expressionISOBAX (Homo sapiens)6480464CTDCalcifediol results in decreased expression of BAX mRNA; Calcifediol results in decreased expression of BAX proteinPMID:21542014
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTDKetoconazole inhibits the reaction [Calcifediol results in decreased expression of BAX mRNA]PMID:21542014
Go Back to source page   Continue to Ontology report