GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | decreases expression | EXP | | 6480464 | CTD | Morphine results in decreased expression of BAX mRNA | PMID:15183518 | Bax | increases expression | EXP | | 6480464 | CTD | Morphine results in increased expression of BAX mRNA; Morphine results in increased expression of BAX protein | PMID:12196588 PMID:18976035 | Bax | multiple interactions | EXP | | 6480464 | CTD | Lithium inhibits the reaction [Morphine results in increased expression of BAX mRNA] | PMID:18976035 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Morphine results in increased expression of BAX protein | PMID:10809959 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Morphine results in increased expression of BAX protein | PMID:10534122 PMID:19070643 PMID:21483469 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | TGFB1 protein affects the reaction [Morphine results in increased expression of BAX protein] | PMID:10809959 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [[Morphine results in increased expression of BAX protein] co-treated with [Morphine results in decreased expression of BCL2 protein]] results in increased activity of CASP3 protein; [Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BAX protein; Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]; Morphine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]]; PDGFB protein inhibits the reaction [Morphine results in increased expression of BAX protein] | PMID:10534122 PMID:12702572 PMID:12927789 PMID:17542780 PMID:21483469 | |
Go Back to source page | Continue to Ontology report |