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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:6704
Term: mebendazole
Definition: A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Chemical ID: MESH:D008463
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[Mebendazole results in increased phosphorylation of BCL2 protein] inhibits the reaction [BCL2 protein binds to BAX protein]PMID:18667591
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