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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:60799
Term: esketamine
Definition: The S- (more active) enantiomer of ketamine.
Chemical ID: MESH:C000629870
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxaffects expressionISOBAX (Homo sapiens)6480464CTDEsketamine affects the expression of BAX mRNAPMID:38219984
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDEsketamine results in increased expression of BAX proteinPMID:38219984
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTDEIF2AK3 protein affects the reaction [Esketamine affects the expression of BAX mRNA]; N-Methylaspartate affects the reaction [Esketamine affects the expression of BAX mRNA]PMID:38219984
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