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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:51397
Term: 1,3-dinitrobenzene
Definition: A dinitrobenzene that is benzene disubstituted at positions 1 and 3 with nitro groups.
Chemical ID: MESH:C017906
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTD3-dinitrobenzene results in increased expression of BAX mRNAPMID:16025311
Baxincreases expressionISOBax (Mus musculus)6480464CTD3-dinitrobenzene results in increased expression of BAX mRNA; 3-dinitrobenzene results in increased expression of BAX proteinPMID:19477251
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