GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atp2a2 | affects response to substance | EXP | | 6480464 | CTD | ATP2A2 protein affects the susceptibility to Phenylephrine | PMID:21952229 | Atp2a2 | decreases activity | EXP | | 6480464 | CTD | Phenylephrine results in decreased activity of ATP2A2 protein | PMID:17287366 | Atp2a2 | decreases expression | EXP | | 6480464 | CTD | Phenylephrine results in decreased expression of ATP2A2 mRNA; Phenylephrine results in decreased expression of ATP2A2 protein | PMID:11577024 PMID:15795322 PMID:17287366 PMID:17592507 PMID:19244478 PMID:23939492 | Atp2a2 | increases expression | EXP | | 6480464 | CTD | Phenylephrine results in increased expression of ATP2A2 mRNA | PMID:16236312 | Atp2a2 | multiple interactions | EXP | | 6480464 | CTD | (+)-JQ1 compound inhibits the reaction [Phenylephrine results in decreased expression of ATP2A2 mRNA]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Phenylephrine results in increased expression of ATP2A2 protein]; [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; Prazosin inhibits the reaction [Phenylephrine results in decreased expression of ATP2A2 mRNA]; THRB protein affects the reaction [Phenylephrine results in decreased expression of ATP2A2 protein]; Triiodothyronine inhibits the reaction [Phenylephrine results in decreased expression of ATP2A2 mRNA] | PMID:11577024 PMID:16236312 PMID:17592507 PMID:19244478 PMID:23939492 | Atp2a2 | multiple interactions | ISO | Atp2a2 (Mus musculus) | 6480464 | CTD | [Phenylephrine co-treated with ADRA1B protein] results in decreased expression of ATP2A2 protein | PMID:11499749 | |
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