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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2168
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp1a2
Name: ATPase Na+/K+ transporting subunit alpha 2
Acc ID: CHEBI:4903
Term: 17alpha-ethynylestradiol
Definition: A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.
Chemical ID: MESH:D004997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp1a2affects expressionEXP 6480464CTDEthinyl Estradiol affects the expression of ATP1A2 mRNAPMID:20170705 PMID:26865667
Atp1a2decreases expressionEXP 6480464CTDEthinyl Estradiol results in decreased expression of ATP1A2 mRNAPMID:15834898 PMID:17351261 PMID:17557909
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