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GENE - TERM ANNOTATION REPORT

RGD ID: 2153
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Acc ID: GO:0004879
Term: nuclear receptor activity
Definition: A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytosol, which leads to its translocation to the nucleus.
Definition Source(s): GOC:txnOH-2018, PMID:23457262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arntcontributes_toISOArnt (Mus musculus)1624291RGDMGI:2176696 PMID:11043581

PMID:11043581
Arntcontributes_toISOARNT (Homo sapiens)1624291RGD PMID:34521881

PMID:34521881
ArntenablesIEAUniProtKB:P27540 or ensembl:ENSP000003514071600115EnsemblGO_REF:0000107

GO_REF:0000107
ArntenablesIEAUniProtKB:P53762 or ensembl:ENSMUSP000000998101600115EnsemblGO_REF:0000107

GO_REF:0000107
Arntcontributes_toISSUniProtKB:P275401600115UniProtGO_REF:0000024

GO_REF:0000024
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