GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | multiple interactions | ISO | RGD:10189 | 6480464 | CTD | ARNT affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA], ARNT promotes the reaction [beta-Naphthoflavone results in decreased abundance of Lactic Acid], beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein], beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein], kaempferol inhibits the reaction [beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]], kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]] | PMID:17012224, PMID:21849270 | multiple interactions | ISO | RGD:732739 | 6480464 | CTD | AHR gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]], beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein], beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein] | PMID:19901195, PMID:21127131, PMID:24486526 | |
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