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GENE - TERM ANNOTATION REPORT

RGD ID: 2139
Species: Rattus norvegicus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: GO:0045121
Term: membrane raft
Definition: Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
Definition Source(s): PMID:16645198, PMID:20044567
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Applocated_inISOAPP (Homo sapiens)1624291RGD PMID:24499793

PMID:24499793
Applocated_inIEAUniProtKB:P05067 or ensembl:ENSP000002849811600115EnsemblGO_REF:0000107

GO_REF:0000107
Appis_active_inIBAPANTHER:PTN002749606 or UniProtKB:P050671600115GO_CentralGO_REF:0000033

GO_REF:0000033
Applocated_inIEAPANTHER:PTHR23103:SF71600115TreeGrafterGO_REF:0000118

GO_REF:0000118
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