GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Apoe | affects response to substance | ISO | Apoe (Mus musculus) | 6480464 | CTD | APOE protein affects the susceptibility to Arsenic | PMID:22719926 | Apoe | increases expression | ISO | Apoe (Mus musculus) | 6480464 | CTD | Arsenic results in increased expression of APOE mRNA | PMID:24019935 | Apoe | increases response to substance | ISO | Apoe (Mus musculus) | 6480464 | CTD | APOE gene mutant form results in increased susceptibility to Arsenic | PMID:22956628 | Apoe | increases response to substance | ISO | APOE (Homo sapiens) | 6480464 | CTD | APOE polymorphism results in increased susceptibility to Arsenic | PMID:18022660 | Apoe | multiple interactions | ISO | Apoe (Mus musculus) | 6480464 | CTD | [APOE protein affects the susceptibility to Arsenic] which affects the expression of AQP1 mRNA; [APOE protein affects the susceptibility to Arsenic] which affects the expression of CDCA5 mRNA; [APOE protein affects the susceptibility to Arsenic] which affects the expression of CYP7A1 mRNA; [APOE protein affects the susceptibility to Arsenic] which affects the expression of GSTA4 mRNA; [APOE protein affects the susceptibility to Arsenic] which affects the expression of LEF1 mRNA; [APOE protein affects the susceptibility to Arsenic] which affects the expression of NUBP1 mRNA; [APOE protein affects the susceptibility to Arsenic] which affects the expression of UGDH mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR10A mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR149 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR15B mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR184 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR188 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR193A mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR211 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR222 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR337 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR376A mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR412 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR467B mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR497 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR592 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR679 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR681 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIR719 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in decreased expression of MIRLET7D mRNA; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of HSPA1B mRNA; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of HSPA1B protein; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of HSPA8 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of MIR211 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of MIR294 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of MIR361 mRNA; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of PELO mRNA; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of SREBF1 protein; [APOE protein affects the susceptibility to Arsenic] which results in increased expression of TNF mRNA | PMID:22719926 | | ||||||||||||||||||||||
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