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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2138
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apoe
Name: apolipoprotein E
Acc ID: CHEBI:28925
Term: mechlorethamine
Definition: A nitrogen mustard that has formula C5H11Cl2N.
Chemical ID: MESH:D008466
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoeincreases expressionEXP 6480464CTDMechlorethamine results in increased expression of APOE mRNAPMID:26273949 PMID:28184907
Apoemultiple interactionsEXP 6480464CTDValproic Acid promotes the reaction [Mechlorethamine results in increased expression of APOE mRNA]PMID:28184907
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