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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2120
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Anxa5
Name: annexin A5
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Anxa5increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of ANXA5 mRNA; Diethylnitrosamine results in increased expression of ANXA5 proteinPMID:19638242 PMID:20935162
Anxa5multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA5 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA5 protein; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA5 mRNAPMID:18164116 PMID:20935162 PMID:28943392
Anxa5multiple interactionsISOAnxa5 (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNAPMID:17917374
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