GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Alpl | increases expression | ISO | ALPL (Homo sapiens) | 6480464 | CTD | Calcitriol results in increased expression of ALPL mRNA; Calcitriol results in increased expression of ALPL protein | PMID:12016462 PMID:21542014 PMID:28105418 | Alpl | multiple interactions | ISO | Alpl (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]]; Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]]; Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]] | PMID:33450223 | |
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