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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2100
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alpl
Name: alkaline phosphatase, biomineralization associated
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alpldecreases expressionEXP 6480464CTDGlucose results in decreased expression of ALPL mRNAPMID:32643284
Alplmultiple interactionsEXP 6480464CTDmorroniside inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]PMID:32643284
Alpldecreases expressionISOAlpl (Mus musculus)6480464CTDGlucose results in decreased expression of ALPL mRNAPMID:33450223
Alplmultiple interactionsISOAlpl (Mus musculus)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]]; Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]]; Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]]PMID:33450223
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