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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2100
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alpl
Name: alkaline phosphatase, biomineralization associated
Acc ID: CHEBI:28197
Term: daidzein
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4'.
Chemical ID: MESH:C004742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alplmultiple interactionsISOALPL (Homo sapiens)6480464CTD[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein]PMID:12650720
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