GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Aldh3a1 | affects expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of ALDH3A1 mRNA | PMID:22298810 | Aldh3a1 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA; Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 protein | PMID:1416978 PMID:16054898 PMID:16497791 PMID:16548065 PMID:18178546 PMID:18796159 PMID:1953764 PMID:20959002 PMID:21215274 PMID:21724226 PMID:24046277 PMID:24355419 PMID:26232522 PMID:29738842 PMID:32109520 PMID:34747641 | Aldh3a1 | multiple interactions | EXP | | 6480464 | CTD | Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA]; Puromycin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of ALDH3A1 protein | PMID:1416978 PMID:1953764 | Aldh3a1 | affects expression | ISO | ALDH3A1 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of ALDH3A1 mRNA | PMID:22298810 | Aldh3a1 | affects expression | ISO | Aldh3a1 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of ALDH3A1 mRNA | PMID:21570461 PMID:26377647 | Aldh3a1 | increases activity | ISO | Aldh3a1 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased activity of ALDH3A1 protein | PMID:7828219 PMID:7955076 | Aldh3a1 | increases expression | ISO | ALDH3A1 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA | PMID:12377990 PMID:15345368 PMID:17517823 PMID:19619570 PMID:19692669 PMID:20106945 PMID:21632981 PMID:26159488 PMID:29738842 | Aldh3a1 | increases expression | ISO | Aldh3a1 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA | PMID:10677587 PMID:1416978 PMID:15034205 PMID:15667827 PMID:16120747 PMID:16467188 PMID:17998271 PMID:18691609 PMID:19933214 PMID:23994337 PMID:24519526 PMID:29738842 PMID:32553695 PMID:7828219 PMID:8148869 PMID:9496914 | Aldh3a1 | multiple interactions | ISO | ALDH3A1 (Homo sapiens) | 6480464 | CTD | [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of ALDH3A1 mRNA; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ALDH3A1 mRNA; [Tetrachlorodibenzodioxin co-treated with AHR mRNA] affects the expression of ALDH3A1 mRNA | PMID:19619570 PMID:20619336 PMID:26159488 | Aldh3a1 | multiple interactions | ISO | Aldh3a1 (Mus musculus) | 6480464 | CTD | AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA]; ARNT protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA]; CHUK protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA]; Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA]; Tetrachlorodibenzodioxin affects the reaction [AHR protein binds to ALDH3A1 promoter] | PMID:1416978 PMID:18691609 PMID:19654925 PMID:24519526 PMID:7828219 | | ||||||||||||||||||||||
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