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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2088
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh3a1
Name: aldehyde dehydrogenase 3 family, member A1
Acc ID: CHEBI:44215
Term: NAD zwitterion
Definition: A NAD that has formula C21H27N7O14P2.
Chemical ID: MESH:D009243
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh3a1increases activityISOAldh3a1 (Mus musculus)6480464CTDNAD results in increased activity of ALDH3A1 proteinPMID:21256123
Aldh3a1multiple interactionsISOALDH3A1 (Homo sapiens)6480464CTD[ALDH3A1 protein co-treated with NAD] results in increased oxidation of aldophosphamide; [ALDH3A1 protein co-treated with NAD] results in increased oxidation of benzaldehydePMID:10856427
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