GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Alb | decreases expression | EXP | | 6480464 | CTD | Acetaminophen results in decreased expression of ALB protein | PMID:20804811 PMID:30794797 PMID:33350580 | Alb | increases expression | EXP | | 6480464 | CTD | Acetaminophen results in increased expression of ALB mRNA | PMID:12883083 PMID:18779383 PMID:23288050 PMID:26962055 | Alb | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; chrysin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Quercetin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein] | PMID:20804811 PMID:30794797 | Alb | decreases expression | ISO | Alb (Mus musculus) | 6480464 | CTD | Acetaminophen results in decreased expression of ALB protein | PMID:31967706 PMID:32040233 PMID:33022361 | Alb | decreases expression | ISO | ALB (Homo sapiens) | 6480464 | CTD | Acetaminophen results in decreased expression of ALB mRNA; Acetaminophen results in decreased expression of ALB protein | PMID:21420995 PMID:24685772 PMID:27761495 PMID:29067470 PMID:32112222 | Alb | decreases secretion | ISO | Alb (Mus musculus) | 6480464 | CTD | Acetaminophen results in decreased secretion of ALB protein | PMID:27161652 PMID:29697884 | Alb | increases expression | ISO | Alb (Mus musculus) | 6480464 | CTD | Acetaminophen results in increased expression of ALB mRNA | PMID:23358195 | Alb | increases expression | ISO | ALB (Homo sapiens) | 6480464 | CTD | Acetaminophen results in increased expression of ALB mRNA | PMID:26690555 PMID:26962055 PMID:27761495 | Alb | multiple interactions | ISO | Alb (Mus musculus) | 6480464 | CTD | [CTH gene mutant form results in increased susceptibility to Acetaminophen] which results in increased expression of ALB protein; allicin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Biflavonoids inhibits the reaction [Acetaminophen results in decreased secretion of ALB protein]; Irbesartan inhibits the reaction [Acetaminophen results in increased expression of ALB protein]; lophirone B inhibits the reaction [Acetaminophen results in decreased secretion of ALB protein]; lophirone C inhibits the reaction [Acetaminophen results in decreased secretion of ALB protein] | PMID:25499718 PMID:27161652 PMID:29697884 PMID:31967706 PMID:32040233 | Alb | multiple interactions | ISO | ALB (Homo sapiens) | 6480464 | CTD | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of ALB mRNA; ALB protein inhibits the reaction [Acetaminophen results in increased abundance of Aldosterone]; ALB protein inhibits the reaction [Acetaminophen results in increased activity of REN protein] | PMID:1825077 PMID:33819548 | | ||||||||||||||||||||||
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