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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2085
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alb
Name: albumin
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Albdecreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of ALB mRNA; Carbon Tetrachloride results in decreased expression of ALB proteinPMID:12867299 PMID:15673190 PMID:16688827 PMID:16872305 PMID:16880627 PMID:17158861 PMID:17278221 PMID:17468546 PMID:17485851 PMID:18418968 PMID:22563491 PMID:23146752 PMID:23500774 PMID:27590029 PMID:30719803 PMID:31150632
Albdecreases secretionEXP 6480464CTDCarbon Tetrachloride results in decreased secretion of ALB proteinPMID:29251412
Albincreases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of ALB proteinPMID:23146695
Albmultiple interactionsEXP 6480464CTD[Carbon Tetrachloride co-treated with Azathioprine] results in decreased expression of ALB protein; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; Colchicine inhibits the reaction [Carbon Tetrachloride results in increased expression of ALB protein]; Colforsin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; danggui buxue decoction inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; Limonene inhibits the reaction [Carbon Tetrachloride results in decreased secretion of ALB protein]; Perindopril inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of ALB protein]; Rivaroxaban inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; saikosaponin D inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB mRNA]; Valsartan inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]PMID:15673190 PMID:16872305 PMID:17278221 PMID:18418968 PMID:23146695 PMID:23146752 PMID:23500774 PMID:27590029 PMID:29251412 PMID:30719803 PMID:31150632 PMID:8614026
Albdecreases expressionISOAlb (Mus musculus)6480464CTDCarbon Tetrachloride results in decreased expression of ALB proteinPMID:27318789 PMID:31697926
Albincreases expressionISOAlb (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of ALB mRNA; Carbon Tetrachloride results in increased expression of ALB proteinPMID:12560238 PMID:17484886
Albmultiple interactionsISOAlb (Mus musculus)6480464CTD[Carbon Tetrachloride co-treated with Phenobarbital] results in increased expression of ALB protein; ginkgolide A inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]; puerarin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]PMID:16233854 PMID:27318789 PMID:31697926
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