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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2084
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alas2
Name: 5'-aminolevulinate synthase 2
Acc ID: CHEBI:31355
Term: carboplatin
Definition: A platinum coordination entity with cis square-planar geometry in which platinum(II) is coordinated to two ammonia ligands and a bidentate cyclobutane-1,1-dicarboxylate ligand.
Chemical ID: MESH:D016190
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alas2decreases expressionEXP 6480464CTDCarboplatin results in decreased expression of ALAS2 mRNAPMID:21296123
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