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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2083
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alad
Name: aminolevulinate dehydratase
Acc ID: CHEBI:16494
Term: lipoic acid
Definition: A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position.
Chemical ID: MESH:D008063
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aladmultiple interactionsEXP 6480464CTDThioctic Acid inhibits the reaction [gallium arsenide results in decreased activity of ALAD protein]; Thioctic Acid inhibits the reaction [Pilocarpine results in decreased expression of ALAD protein]PMID:19798568 PMID:20026167 PMID:20584200 PMID:21783994
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