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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:17620
Term: ferulic acid
Definition: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.
Chemical ID: MESH:C004999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1multiple interactionsEXP 6480464CTDferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]]PMID:35110471
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