GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | decreases phosphorylation | EXP | | 6480464 | CTD | Palmitic Acid results in decreased phosphorylation of AKT1 protein | PMID:22819839 | Akt1 | multiple interactions | EXP | | 6480464 | CTD | 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; geniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] | PMID:22713545 PMID:22819839 PMID:25109277 | Akt1 | decreases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Palmitic Acid results in decreased phosphorylation of AKT1 protein | PMID:35747990 | Akt1 | increases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Palmitic Acid results in increased phosphorylation of AKT1 protein | PMID:32283200 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; [Palmitic Acid co-treated with Arsenic] affects the expression of AKT1 mRNA; [Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein; Agmatine inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]; albiflorin inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein]; dorsomorphin inhibits the reaction [Agmatine inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Palmitic Acid inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; STF 083010 inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; zhenwu decoction inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein] | PMID:22683933 PMID:30362509 PMID:32283200 PMID:33736254 PMID:35747990 PMID:37523837 | Akt1 | multiple interactions | ISO | Akt1 (Mus musculus) | 6480464 | CTD | [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of AKT1 protein | PMID:26847930 | | ||||||||||||||||||||||
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