GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ahr | multiple interactions | EXP | | 6480464 | CTD | [resveratrol binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to sunitinib; [SB 203580 binds to and results in increased activity of AHR protein] which results in increased susceptibility to sunitinib | PMID:24247421 | Ahr | increases activity | ISO | AHR (Homo sapiens) | 6480464 | CTD | sunitinib results in increased activity of AHR protein | PMID:23288144 | Ahr | multiple interactions | ISO | AHR (Homo sapiens) | 6480464 | CTD | [resveratrol results in decreased activity of AHR protein] inhibits the reaction [sunitinib results in increased expression of CYP1A1 mRNA]; [sunitinib results in increased activity of AHR protein] which results in increased expression of CYP1A1 | PMID:23288144 | | ||||||||||||||||||||||
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